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Tadalafil Tablets
Tadalis SX

  • Tadalafil Tablets
  • ED040
  • In Stock

Premium High Quality Product & Original Active Substance!

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   Manufacturer's Suggested Retail Price (MSRP) per pill is $6.74 ! Buying from us will save you at least 48.22%

Package per pill Price SAVINGS BONUS Order
20mg * 12 pills
$3.49 $41.88 $0.00
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SILVER BONUS
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20mg * 24 pills
$2.36 $56.64 $27.12
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SILVER BONUS
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20mg * 36 pills
$2.14 $77.04 $48.60
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SILVER BONUS
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20mg * 48 pills
$2.05 $98.40 $69.12
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SILVER BONUS
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20mg * 64 pills
$1.95 $124.80 $98.56
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SILVER BONUS
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20mg * 96 pills
$1.74 $167.04 $168.00
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SILVER BONUS
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20mg * 128 pills
$1.63 $208.64 $238.08
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SILVER BONUS
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Tadalafil is an orally administered drug used to treat male erectile dysfunction (impotence). It is marketed worldwide under the brand name Cialis. It is a phosphodiesterase 5 (PDE5) inhibitor.

Tadalafil's distinguishing pharmacologic feature is its longer half-life (17.5 hours) compared with Viagra and Levitra (4-5 hours). This longer half-life results in a longer duration of action and is, in part, responsible for the Cialis nickname of the "weekend pill." This longer half-life also is the basis of current investigation for tadalafil's use in pulmonary arterial hypertension as a once-daily therapy.

Tadalafil tablets are indicated for the treatment of: erectile dysfunction (ED), the signs and symptoms of benign prostatic hyperplasia (BPH), the signs and symptoms of BPH (ED/BPH).

Tadalis SX is available in the form of classic tablets of oblong form, coated and wrapped in blisters for two tablets. Each tablet contains 20 mg of tadalafil. Unlike many other drugs that improve male potency, each pack of the Cialis analogue Tadalis SX contains not one but two tablets at once, which makes the purchase of this medicine even more economical. For most men, the initial recommended dose of Tadalis SX is 10 mg. This dosage, if necessary, can be increased to 20 mg or reduced to 5 mg. The tablet is taken 30-50 minutes before the planned sexual intercourse, washed down with a small amount of water. The effect of the drug begins 15 to 20 minutes after its administration and persists for the next 36 hours.

Tadalafil is used to treat male erectile dysfunction (impotence) and pulmonary arterial hypertension (PAH). Part of the physiological process of erection involves the release of nitric oxide (NO) in the corpus cavernosum.

This then activates the enzyme guanylate cyclase which results in increased levels of cyclic guanosine monophosphate (cGMP), leading to smooth muscle relaxation in the corpus cavernosum, resulting in increased inflow of blood and an erection. Tadalafil is a potent and selective inhibitor of cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum.

This means that, with tadalafil on board, normal sexual stimulation leads to increased levels of cGMP in the corpus cavernosum which leads to better erections. Without sexual stimulation and no activation of the NO/cGMP system, tadalafil should not cause an erection.

Tadalafil inhibits the cGMP specific phosphodiesterase type 5 (PDE5) which is responsible for degradation of cGMP in the corpus cavernosum located around the penis. Penile erection during sexual stimulation is caused by increased penile blood flow resulting from the relaxation of penile arteries and corpus cavernosal smooth muscle.

This response is mediated by the release of nitric oxide (NO) from nerve terminals and endothelial cells, which stimulates the synthesis of cGMP in smooth muscle cells. Cyclic GMP causes smooth muscle relaxation and increased blood flow into the corpus cavernosum. The inhibition of phosphodiesterase type 5 (PDE5) by tadalafil enhances erectile function by increasing the amount of cGMP.

Metabolism: Tadalafil is predominantly metabolized by CYP3A4 to a catechol metabolite. The catechol metabolite undergoes extensive methylation and glucuronidation to form the methylcatechol and methylcatechol glucuronide conjugate, respectively. In vitro data suggests the metabolites are not expected to be pharmacologically active at observed metabolite concentrations.

Absorption: After single oral-dose administration, the maximum observed plasma concentration (Cmax) of tadalafil is achieved between 30 minutes and 6 hours (median time of 2 hours). Absolute bioavailability of tadalafil following oral dosing has not been determined.

Route of elimination: Tadalafil is excreted predominantly as metabolites, mainly in the feces (approximately 61% of the dose) and to a lesser extent in the urine (approximately 36% of the dose).

Half life: 17.5 hours

All medicines may cause side effects, but many people have no, or minor, side effects.Some medical conditions may interact with Tadalafil.

Tell your doctor or pharmacist if you have any medical conditions.

Common tadalafil side effects may include: headache, flushing (warmth, redness, or tingly feeling), nausea, upset stomach, stuffy nose; or muscle pain, back pain, pain in your arms or legs.

This is not a complete list of all side effects that may occur. If you have questions about side effects, contact your health care provider.

Viktor
21/Jul/2024

I've been taking 20mg Tadalis SX for the last six months. I can't say enough about how much it has helped with erectile dysfunction. Erections are firm and last long enough for two orgasms. I've discovered something else while taking Tadalis SX. I have been dealing with symptoms of depression for several years. I've tried several of the anti-depressant medications but had terrible side effects. Not to mention, it made the performance issue worse. Since taking Tadalis SX I've noticed my depression has all but disappeared. I did some research and discovered that some studies have reported that Tadalafil has helped with depression in men. I've got my life back and feel great.

Luca
21/Jul/2024

I'm a 30 year old male. I've suffered from ED since becoming sexually active. Sildenafil was a big help but even at a low dosage I found the side effects intense, nasal congestion and headaches, often so intrusive they ruined the sex. I've tried Tadalafil - Tadalis SX - a couple of times now. At a dosage of 20mg it keeps me in a state of almost constant arousal, complete with spontaneous erections at embarrassing times, for 30hr. My dosage is obviously way too high and I will lower it but at this high level I have suffered no side effects, amazing! The sex is very natural, I am really very impressed .

James
12/Jan/2024

I'm 37 and have been using Tadalis SX for five years. 20mg dose and WOW!!! It takes me about 2 hours to start feeling the effects and works best after 4 hours. Erections are hard as a rock. It's ~$2 for one 20mg pill guys when you take it with discounts. Thinking of going to Mexico and let them know they should buy from RxMedWorld too than resell to USA... heh. The wife and I have sex almost every day and sometimes twice a day.

Mel
08/Mar/2023

Tried Tadalis SX after talking to my wife about our problem... meds were received on time. Twelve hours later nothing was feeling down then around twenty hours later bingo it started to work, had sex several times over a 3 day period and it is still working on day four, wife very impressed states it is harder bigger and last longer than when I was younger.

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